The evolutionary origin of RNA stem structures and the preservation of their base-pairing under a spontaneous and random mutation process have puzzled theoretical evolutionary biologists. DNA replication-related template switching is a mutation mechanism that creates reverse-complement copies of sequence regions within a genome by replicating briefly along either the complementary or nascent DNA strand. Depending […]
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Reasonableness of GRK Antibodies for Individual Detection and Quantification of GRK Isoforms in Western Blots.
G protein-coupled receptors (GPCRs) are controlled by GPCR kinases (GRKs) which phosphorylate intracellular spaces of the dynamic receptor. This outcome in the enrollment of arrestins, prompting desensitization and disguise of the GPCR. Beside following up on GPCRs, GRKs manage an assortment of layer, cytosolic, and atomic proteins by means of phosphorylation as well as by […]
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