Template switching in DNA replication can create and maintain RNA hairpins.

The evolutionary origin of RNA stem structures and the preservation of their base-pairing under a spontaneous and random mutation process have puzzled theoretical evolutionary biologists. DNA replication-related template switching is a mutation mechanism that creates reverse-complement copies of sequence regions within a genome by replicating briefly along either the complementary or nascent DNA strand. Depending […]

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labprotocol

Expression modifications of cytotoxicity and apoptosis genes in HTLV-1-associated myelopathy/tropical spastic paraparesis

Genetic variations in autoimmune genes and VKH illness Goal: Vogt-Koyanagi-Harada (VKH) illness is a uncommon autoimmune illness. The autoimmune response in VKH illness is in opposition to the melanin-producing cells; due to this fact, in affected people melanocyte-containing organs manifest illness signs together with eyes, ears, pores and skin and nervous system. VKH is a multifactorial illness, and […]

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