The evolutionary origin of RNA stem structures and the preservation of their base-pairing under a spontaneous and random mutation process have puzzled theoretical evolutionary biologists. DNA replication-related template switching is a mutation mechanism that creates reverse-complement copies of sequence regions within a genome by replicating briefly along either the complementary or nascent DNA strand. Depending […]Read More
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Appropriateness of GRK Antibodies for Individual Detection and Quantification of GRK Isoforms in Western Blots.
G protein-coupled receptors (GPCRs) are controlled by GPCR kinases (GRKs) which phosphorylate intracellular spaces of the dynamic receptor. This outcome in the enlistment of arrestins, prompting desensitization and disguise of the GPCR. Beside following up on GPCRs, GRKs direct an assortment of film, cytosolic, and atomic proteins through phosphorylation as well as by going about […]Read More